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Anabolic effects of clenbuterol after long-term treatment and withdrawal in t the rat Injection of rats with the beta 2-adrenoceptor agonist clenbuterol (1 mg/kg/d for 15 days) stimulated an increase in body weight (9%) and protein (8%) and water (7%) content, but reduced food intake (4%) and epididymal fat pad mass (39%). Clenbuterol-fed rats (2 mg/kg diet for 10 days, providing an average of 0. 04 mg clenbuterol/kg/d) increased body weight (7%), muscle mass (15% to 21%), and muscle protein content (9% to 26%), whereas epididymal fat pad weight and muscle glycogen content were reduced. Abstract The potent anabolic effects of the beta 2-adrenoceptor agonist clenbuterol on skeletal muscle have been reported to be independent of actions on beta-adrenoceptors. The potent anabolic effects of the beta 2-adrenoceptor agonist clenbuterol on skeletal muscle have been reported to be independent of actions on beta-adrenoceptors. Clenbuterol is lipophilic and is known to have direct intracellular actions (1). Although the anabolic effects of clenbuterol administration have previously been shown to be 2-AR mediated (6), the same cannot be assumed for clenbuterol’s myotoxic effects. To investi-gate whether clenbuterol-induced necrosis was recep-. These effects include increased heart rate and blood pressure, improved oxygen uptake and delivery, and increased metabolism and thermogenesis. Clenbuterol has also been shown to have anabolic properties by promoting muscle protein synthesis and increasing lean muscle mass chinarus.online/2023/07/11/clenbuterol-2019-clenbuterol-hcl-astralean-60-mcg/
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